A charter flight crashed Saturday afternoon in Canada's Arctic, killing 12 people and injuring three others, First Air said.

The Boeing 737-200, en route to Resolute Bay from Yellowknife, went down roughly 10 minutes after its last reported communication, according to the airline. Eleven passengers and four crew members were on board.

The three survivors were being treated at a medical center, said First Air, based in Kanata, Ontario.

The cause of the crash near the Resolute Bay airport was not immediately known.

Firefighters, medical teams, police and members of the Canadian military were among the first to respond to the accident, according to Dominique Verdon, spokeswoman with the Canada Department of National Defence.

The Transportation Safety Board of Canada will investigate the crash, she said.

CNN's Stephanie Gallman contributed to this report.